|Clomid: Profile, General Information, Stacking and Use
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Pharmaceutical Name: Clomiphene (as citrate)
Molecular weight of base: 405.9663
Molecular weight of ester: 192.125 (citric acid, 6 carbons)
Clomid is generally considered the anti-estrogen of choice for improving recovering of natural levels of testosterone production after a cycle in which those levels have been suppressed for the duration. Clomid is also effective for improving testosterone production of endurance athletes and is effective at reducing the risk of gynecomastia during a cycle when the use of aromatizing steroids have been used. However, the anti-estrogen of choice for the express purpose of reducing or eliminating gyno symptoms is clomid's counterpart nolvadex, since it is spefically designed to prevent estrogen from binding at receptor sites. Neverthless, clomid can be used for this purpose with a good deal of success.
Clomid's effectiveness is achieved not by stimulation of the hypothalamus and pituitary, but by blocking their inhibition by estrogen.
Clomid is referred to as a "mixed estrogen agonist / antagonist" and when bound to the estrogen receptor, puts it in a somewhat different shape than does estradiol (an estrogen derivative). When using clomid as an anti-estrogen, the cofactor used in the tissue cannot bind and so the estrogen receptor remains inactive. In this case, clomid acts as an agonist.
Clomid is an effective agonist in the bone tissue and can improve blood cholesterol levels.
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Clomid is normally used for post cycle therapy ran as follows:
Standard Clomid Post Cycle Therapy
Day 1 - 300mg
Day 2-11 - 100mg/day
Day 12-21 - 50mg/day
Note that when you commence post cycle therapy depends on which steroids you have used during your cycle and their related characteristics.
If used as an on-cycle anti-estrogen, 100-150 mg of clomid can be used when symptoms of gyno are seen and until a few days after symptoms subside. This should keep gyno under control.
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